Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Visit old site
Home Print this page Email this page Small font size Default font size Increase font size
Users Online: 1017
ORIGINAL ARTICLE
Year : 2014  |  Volume : 6  |  Issue : 10  |  Page : 519-531

Thimerosal-containing hepatitis b vaccination and the risk for diagnosed specific delays in development in the united states: A case-control study in the vaccine safety datalink


1 Institute of Chronic Illnesses, Inc, Silver Spring, Maryland, USA
2 Institute of Chronic Illnesses, Inc, Silver Spring, Maryland; Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas, USA
3 Biology Department, Simpson University, Redding, California, USA
4 CoMeD, Inc, Silver Spring, Maryland, USA

Correspondence Address:
Janet K Kern
Institute of Chronic Illnesses, Inc., 14 Redgate Court, Silver Spring, Maryland - 20905
USA
Login to access the Email id

Source of Support: This study was fi nancially supported by the Dwoskin Family Foundation and the Selz Foundation., Conflict of Interest: All of the investigators on the present study have been involved in vaccine/biologic litigation.


DOI: 10.4103/1947-2714.143284

Rights and Permissions

Background: Within the first 3 years of life, the brain develops rapidly. Its development is characterized by critical developmental periods for speech, vision, hearing, language, balance, etc.; and alteration in any of the processes occurring in those critical periods can lead to specific delays in development. Aims: The present study evaluated the potential toxic effects of organic-mercury exposure from Thimerosal (49.55% mercury by weight) in childhood vaccines and its hypothesized possible relationship with specific delays in development. Materials and Methods: A hypothesis testing case-control study was undertaken to evaluate the relationship between exposure to Thimerosal-containing hepatitis B vaccines administered at specific intervals in the first 6 months among cases diagnosed with specific delays in development and controls born between 1991-2000, utilizing data in the Vaccine Safety Datalink database. Results: Cases were significantly more likely than controls to have received increased organic-mercury from Thimerosal-containing hepatitis B vaccine administered in the first, second, and sixth month of life. Conclusion: Though routine childhood vaccination may be an important public health tool to reduce the morbidity and mortality associated with infectious diseases, the present study supports an association between increasing organic-mercury exposure from Thimerosal-containing childhood vaccines and the subsequent risk of specific delays in development among males and females.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed6538    
    Printed56    
    Emailed1    
    PDF Downloaded443    
    Comments [Add]    
    Cited by others 8    

Recommend this journal