Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Visit old site
Home Print this page Email this page Small font size Default font size Increase font size
Users Online: 1293


 
 Table of Contents  
CASE REPORT
Year : 2014  |  Volume : 6  |  Issue : 4  |  Page : 178-180

Ventricular standstill: An uncommon electrophysiological abnormality caused by profound vagal tone


Department of Internal Medicine, Cardiology and Nuclear Cardiology, University of Alabama at Birmingham Health Center Montgomery, Montgomery, Alabama 36116, USA

Date of Web Publication22-Apr-2014

Correspondence Address:
Shikha Jaiswal
2055, East S Blvd, Suite 200, Montgomery, Alabama - 36116
USA
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1947-2714.131245

Rights and Permissions
  Abstract 

Context : Ventricular standstill (VS) is an uncommon electrophysiological phenomenon and usually manifests as syncope. Rarely has a case been reported where the patient has been totally asymptomatic, and it has resolved spontaneously. Case Report : We report a case of complete VS and high-degree atrioventricular (AV) block in a 50-year-old female, who was admitted for nausea, vomiting, and chest pain. The patient never had a syncopal episode, even though she was in VS for more than 10 s. Conclusion : Such degree of conduction abnormality without any syncope has not been reported so far. Her electrophysiological abnormality was attributed to profound vagotonic effect and was treated with a permanent pacemaker.

Keywords: Ventricular standstill, High-degree AV blocks, Syncope, Vagal tone, Pacemaker


How to cite this article:
Jaiswal S, Aldave AN, Wool KJ. Ventricular standstill: An uncommon electrophysiological abnormality caused by profound vagal tone. North Am J Med Sci 2014;6:178-80

How to cite this URL:
Jaiswal S, Aldave AN, Wool KJ. Ventricular standstill: An uncommon electrophysiological abnormality caused by profound vagal tone. North Am J Med Sci [serial online] 2014 [cited 2020 May 31];6:178-80. Available from: http://www.najms.org/text.asp?2014/6/4/178/131245


  Introduction Top


Ventricular standstill (VS) is a rare electrophysiological abnormality. The name describes what happens - the heart stops beating and stands perfectly still. No blood is pumped and the results are the same as ventricular fibrillation (VFib). Both VS and VFib present as syncope and sometimes even as sudden cardiac death. However, VS is about 10 times more dangerous than VFib. [1] VS appears as P waves, without accompanying QRS complexes on telemetry. This occurs because the sinoatrial node is still functional, even though no impulses are passing through to the ventricles. [2]

Here, we describe an uncommon presentation of prolonged episodes VS in a middle-aged female without alteration in mental status or syncope.


  Case Presentation Top


A 50-year-old African American female with a past medical history of uncontrolled hypertension, membranous ventricular septal defect, and nonobstructive coronary artery disease presented with complaints of pressure-like substernal chest pain, nausea, and vomiting of 2-h duration. She complained of constant dry heaves and had three episodes of vomiting while in the emergency room (ER). She also complained of intermittent dizziness, nausea, and vomiting for the past 2 months.

Her vitals on admission were as follows: temperature of 98.6°F, heart rate of 60/min, respiratory rate of 20/min, oxygen saturation 98%, and blood pressure of 209/123 mm Hg. Physical examination was normal except for a systolic murmur along the left sternal border. Initial electrocardiogram (EKG) showed normal sinus rhythm, and initial troponin was 0.01 ng/dl.

While interviewing the patient, her monitor read as asystole on two occasions lasting for 9-11 s [see [Figure 1] and [Figure 2]. She was, however, awake and alert at that time but complaining of nausea. The telemetry strips on detailed examination revealed presence of P waves with very infrequent QRS complexes. This was consistent with VS. The rhythm, however, spontaneously reverted to normal sinus with consistent 1:1 conduction. Hence, despite having no ventricular contraction for about 10 s, she had no symptoms. She was then transferred to telemetry for observation.
Figure 1: First telemetry recording while patient was being interviewed in the ER. ER = emergency room

Click here to view
Figure 2: Second telemetry recording a few minutes later, when patient was sitting in the ER, awake, alert and oriented but complaining of nausea. ER = emergency room

Click here to view


At 5 am the next morning, the on-call physician was informed by the telemetry technician that the patient had been in VS for more than 10 s, which was preceded by a high-degree atrioventricular (AV) block [Figure 3]. Patient was found to be asleep and was totally asymptomatic on waking up. Because this was the third episode of VS, though not accompanied by syncope, we decided to intervene. Her frequent episodes of VS were attributed to increased vagal response from nausea and vomiting as well as REM (rapid eye movement) sleep. In view of this being a marked response, a permanent dual chamber pacemaker was implanted, following which, she remained asymptomatic.
Figure 3: Telemetry recording showing high-degree AV block and VS. VS = ventricular standstill, AV = atrioventricular

Click here to view



  Discussion Top


AV block of high degree is well described in literature and is considered an indication for permanent pacemaker implantation irrespective of symptoms. [3] This is because the level of block is usually in the His-Purkinge system or below, and patients are at a risk of profound bradycardia or asystole. Patients may present with syncope or sudden death and require cardiopulmonary resuscitation (CPR). Surviving a prolonged VS and high-degree AV block, without any medical assistance is rare, and there are only few case reports that document this event. In some cases, ischemic damage to the myocardium produces heart block via damage to the ventricular conduction system.

In our patient, what is remarkable is the fact that she experienced these episodes of prolonged VS, without any syncopal events. This was documented on two different occasions including an episode of more than 10 s of VS while the patient was sleeping. The latter could be attributed to the vagotonic effect of sleep. During REM sleep, sinus arrests and AV blocks unrelated to apnea or hypopnea have been described. [4] It has been hypothesized that REM sleep bradyarrhythmias might be the consequence of either the switch from sympathetic to vagal predominance during the bursts of REM or the withdrawal of sympathetic activity during phasic REM events. [4],[5]

On the other hand, vagal stimulation can also be exceptionally profound in that besides the sinus node, it can inhibit the AV node and even the automaticity of the ventricle. Vagally mediated paroxysmal AV block has been described during tilt test, [6] carotid sinus massage, swallowing, vomiting, and left heart catheterization. [7] Our patient in the past month had experienced off and on dizziness, which may have occurred during episodes of vomiting. This could be attributed to AV block, which presumably was caused by increased vagal tone. Permanent pacing is not a regular indication for vagal-mediated dizziness. However, in this case, as the patient developed high-degree AV block and prolonged episodes of VS, it was clearly indicated.


  Conclusion Top


It is important to be aware that patients with recurrent dizziness but with an initially normal EKG could still have a cardiac etiology, and early detection and appropriate treatment is important for their survival.

There are no definite indications in the current guidelines [8] for permanent pacemaker implantation in patients with VS. Clinical judgment is, therefore, important in these cases, as these electrophysiological abnormalities can sometimes also lead to sudden cardiac death.

 
  References Top

1.Phibbs B. The Human Heart: A basic guide to heart disease. 2 nd edition. Philadelphia, PA: Lippincott Williams and Wilkins; 2007;111-12.  Back to cited text no. 1
    
2.Hammond C. Ventricular fibrillation and standstill. RN 1984;47:120.  Back to cited text no. 2
[PUBMED]    
3.Sidhu M, Singh HP, Chopra AK, Kapila D, Sidhu S. Surviving ventricular standstill for 111 seconds during holter monitoring. Ann Noninvasive Electrocardiol 2012;17:61-2.  Back to cited text no. 3
    
4.Serafini A, Dolso P, Gigli GL, Fratticci L, Cancelli I, Facchin D, et al. Rem sleep brady-arrhythmias: An indication to pacemaker implantation? Sleep Med 2012;13:759-62.  Back to cited text no. 4
    
5.Holty JE, Guilleminault C. REM-related bradyarrhythmia syndrome. Sleep Med Rev 2011;15:143-51.  Back to cited text no. 5
    
6.Pentousis D, Cooper JP, Cobbe SM. Prolonged asystole induced by head up tilt test. Report of four cases and brief review of the prognostic significance and medical management. Heart 1997;77:273-5.  Back to cited text no. 6
    
7.Goethals MA, Kersschot IE, Snoeck J. Ventricular standstill during left heart catheterization. Pacing Clin Electrophysiol 1988;11:123-4.  Back to cited text no. 7
[PUBMED]    
8.Epstein AE, DiMarco JP, Ellenbogen KA, Estes NA 3 rd , Freedman RA, Gettes LS, et. al. ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities. J Am Coll Cardiol 2008; 51:e1-62.  Back to cited text no. 8
    


    Figures

  [Figure 1], [Figure 2], [Figure 3]


This article has been cited by
1 A case of elusive cardiac dysrhythmia in high-risk syncope
Yijia Mu,Mark Supino
The American Journal of Emergency Medicine. 2019; : 158381
[Pubmed] | [DOI]



 

Top
 
 
  Search
 
Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
Access Statistics
Email Alert *
Add to My List *
* Registration required (free)

 
  In this article
Abstract
Introduction
Case Presentation
Discussion
Conclusion
References
Article Figures

 Article Access Statistics
    Viewed2349    
    Printed54    
    Emailed0    
    PDF Downloaded269    
    Comments [Add]    
    Cited by others 1    

Recommend this journal