Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Visit old site
Home Print this page Email this page Small font size Default font size Increase font size
Users Online: 1027
CASE REPORT
Year : 2015  |  Volume : 7  |  Issue : 6  |  Page : 288-290

Hairy cell leukemia presenting with duodenal involvement duodenum: A case report


1 Department of Internal Medicine, Seton Hall University School of Health and Medical Sciences, St Michaels Medical Center, Newark, New Jersey, USA
2 Department of Hematology and Oncology, Seton Hall University School of Health and Medical Sciences, St Michaels Medical Center, Newark, New Jersey, USA

Correspondence Address:
Dr. Hamid Shaaban
Department of Hematology and Oncology, Seton Hall University School of Health and Medical Sciences, St Michaels Medical Center, 111 Central Avenue, Newark - 07102, New Jersey
USA
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1947-2714.157489

Rights and Permissions

Context: A rare case of adult hairy cell leukemia (HCL) with duodenal involvement is presented. Case Report: The patient was a 48-year-old man, who had a history of hairy cell leukemia. Three days after completion of 2-chlorodeoxyadenosine (CDA) chemotherapy, the patient started experiencing abdominal pain. An extensive gastroenterological workup culminated in the patient getting an esophagogastroduodenoscopy (EGD) that revealed duodenal infl ammation and biopsies were taken. The duodenal biopsy was positive for chronic inflammatory infiltrate, primarily consisting of atypical lymphocytes and plasma cells with tartrate-resistant acid phosphatase (TRAP) positivity, and hence a diagnosis of duodenal involvement with HCL was made. Repeat bone marrow biopsy done 2 weeks after finishing chemotherapy revealed residual disease. At the 3-month follow-up, the patient was asymptomatic with a normocellular marrow and no residual disease. Repeat abdomen computerized tomography (CT) scan at completion of therapy showed resolution of duodenal thickening and spleen size of 12 cm. Currently, patient is in clinical remission for 6 years with 4-6 monthly follow-up visits and continues to do well. Conclusion: This case is presented to highlight the first case report of HCL with duodenal involvement that was successfully treated with CDA.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1568    
    Printed40    
    Emailed0    
    PDF Downloaded141    
    Comments [Add]    

Recommend this journal