North American Journal of Medical Sciences

ORIGINAL ARTICLE
Year
: 2010  |  Volume : 2  |  Issue : 10  |  Page : 487--490

Is pseudoexfoliation syndrome associated with coronary artery disease?


Mehmet Yunus Emiroglu1, Erol Coskun2, Hekim Karapinar1, Musa Capkin2, Zekeriya Kaya1, Hasan Kaya1, Mustafa Akcakoyun1, Ramazan Kargin1, Zeki Simsek1, Göksel Acar1, Soe Moe Aung1, Selcuk Pala1, Burak Özdemir2, Ali Metin Esen1, Cevat Kirma1 
1 Department of Cardiology, Kartal Kosuyolu Cardiovascular Research and Training Hospital, Istanbul, Turkey
2 Department of Ophthalmology, Kartal Research and Training Hospital, Istanbul, Turkey

Correspondence Address:
Mehmet Yunus Emiroglu
Kaynarca District, Sevgi Street, No:1/16 Pendik, Istanbul
Turkey

Background: Pseudoexfoliation syndrome (PEX) is recognised by chronic deposition of abnormal pseudoexfoliation material on anterior segment structures of the eye, especially the anterior lens capsule. In recent years, several studies have shown the presence of vascular, cardiac and other organ pseudoexfoliative material in patients with ocular pseudoexfoliation. Aims : The purpose of this study is to determine whether an association exists between ocular pseudoexfoliation and coronary artery disease, aortic aneurysms and peripheric vascular disease. Patients and Methods: 490 patients who underwent coronary angiography (CAG) at Kosuyolu Cardiovascula Research and Training Hospital were included in the study. Patients were evaluated for conventional risk factors such as age, sex, family history, hypertension, diabetes, dislipidemia and smoking. Detailed eye examinations including evaluation of lens were done in all patients. The presence of PEX material in the anterior segment was best appreciated by slit lamp after pupillary dilation. The patients were divided into two groups according to the presence of PEX, and compared for the presence of CAD and other risk factors. Results: CAD was present in 387 patients. 103 patients had normal coronary angiography. 20 (5.2 %) of CAD patients and 4 (3.9%) of normal CAG patients were found to have PEX (p>0.05). There was no significant relationship between CAD and the presence of PEX (p>0.05). When patients were grouped according to the presence of PEX, only age was significantly different between the two groups (r: 0.25, p<0.001). Conclusion: There is no significant relationship between the presence of PEX and CAD. Further studies in larger scales with elderly population may be more valuable.


How to cite this article:
Emiroglu MY, Coskun E, Karapinar H, Capkin M, Kaya Z, Kaya H, Akcakoyun M, Kargin R, Simsek Z, Acar G, Aung SM, Pala S, Özdemir B, Esen AM, Kirma C. Is pseudoexfoliation syndrome associated with coronary artery disease?.North Am J Med Sci 2010;2:487-490


How to cite this URL:
Emiroglu MY, Coskun E, Karapinar H, Capkin M, Kaya Z, Kaya H, Akcakoyun M, Kargin R, Simsek Z, Acar G, Aung SM, Pala S, Özdemir B, Esen AM, Kirma C. Is pseudoexfoliation syndrome associated with coronary artery disease?. North Am J Med Sci [serial online] 2010 [cited 2019 Dec 6 ];2:487-490
Available from: http://www.najms.org/article.asp?issn=1947-2714;year=2010;volume=2;issue=10;spage=487;epage=490;aulast=Emiroglu;type=0