North American Journal of Medical Sciences

CASE REPORT
Year
: 2011  |  Volume : 3  |  Issue : 10  |  Page : 469--471

Vitamin D deficiency in a man with multiple myeloma


Zackariah Clement1, RN Meeghan Ashford2, Seeva Sivakumaran3 
1 Department of Surgery, The Canberra Hospital, Clinical School of Medicine, The Australian National University Medical School, Canberra, Australia
2 Department of Nursing and Midwifery, The Canberra Hospital, Clinical School of Medicine, The Australian National University Medical School, Canberra, Australia
3 Department of Geriatrics, The Canberra Hospital, Clinical School of Medicine, The Australian National University Medical School, Canberra, Australia

Correspondence Address:
Zackariah Clement
Department of Surgery, The Canberra Hospital, Australia. Clinical School of Medicine, The Australian National University Medical School, Canberra
Australia

Context: Vitamin D deficiency is extremely common in multiple myeloma, and it represents a surrogate for clinical multiple myeloma disease status. Patients may complain of dull, persistent, generalized musculoskeletal aches and pains with fatigue or decrease in muscle strength. Case Report: A 63 year old male with multiple myeloma on Bortezomib presented with worsening generalized musculoskeletal pain, weakness, and multiple falls. On initial examination he was pale with a depressed affect. He had resting tremor, generalized bony tenderness, worse on movement and weight bearing, muscle weakness, and a waddling gait. His bone studies showed features of osteomalacia with a very low Vitamin D level of less than 20 nmol/L. He was treated with 3000 units of Vitamin D daily and physiotherapy. After 4 months, although his multiple myeloma deteriorated, there was a significant decrease in his generalized musculoskeletal pain. Conclusions: This case highlights that vitamin D deficiency is common in patients with multiple myeloma, and can cause generalized musculoskeletal pain and increase the risk of falls, yet it often goes unrecognized. In patients with non-specific musculoskeletal pain, and inadequate sun-exposure medical practitioners must have a high index of suspicion for vitamin D deficiency.


How to cite this article:
Clement Z, Meeghan Ashford R N, Sivakumaran S. Vitamin D deficiency in a man with multiple myeloma.North Am J Med Sci 2011;3:469-471


How to cite this URL:
Clement Z, Meeghan Ashford R N, Sivakumaran S. Vitamin D deficiency in a man with multiple myeloma. North Am J Med Sci [serial online] 2011 [cited 2019 Dec 14 ];3:469-471
Available from: http://www.najms.org/article.asp?issn=1947-2714;year=2011;volume=3;issue=10;spage=469;epage=471;aulast=Clement;type=0