North American Journal of Medical Sciences

REVIEW ARTICLE
Year
: 2011  |  Volume : 3  |  Issue : 3  |  Page : 103--106

Hapten may play an important role in food allergen-related intestinal immune inflammation


Zhi-Qiang Liu, Ping-Chang Yang 
 Department of Pathology & Molecular Medicine, McMaster University. Hamilton, ON, Canada

Correspondence Address:
Ping-Chang Yang
Room T3303, 50 Charlton Ave East, St. Joseph Healthcare, Hamilton, ON
Canada

There has been a significant increase in the prevalence of allergic diseases especially over the past 2 to 3 decades. However, the etiology and pathogenesis of food allergy are not fully understood. In recent years, with the huge increase in atopic disease, there has also been an increase in dietary hapten exposure. Allergic reactions to chemical haptens occur, in the overwhelming majority of cases, as an inflammatory reaction in the skin to direct contact with haptens. While reactions to haptens on other epithelial surfaces have only rarely been investigated; it is still not clear whether haptens can combine the food antigens and play a role in the induction of food allergen-related inflammation in the intestine. Further research is needed to reveal the underlying mechanism.


How to cite this article:
Liu ZQ, Yang PC. Hapten may play an important role in food allergen-related intestinal immune inflammation.North Am J Med Sci 2011;3:103-106


How to cite this URL:
Liu ZQ, Yang PC. Hapten may play an important role in food allergen-related intestinal immune inflammation. North Am J Med Sci [serial online] 2011 [cited 2020 Jan 19 ];3:103-106
Available from: http://www.najms.org/article.asp?issn=1947-2714;year=2011;volume=3;issue=3;spage=103;epage=106;aulast=Liu;type=0