North American Journal of Medical Sciences

ORIGINAL ARTICLE
Year
: 2013  |  Volume : 5  |  Issue : 10  |  Page : 594--599

Clinical predictors of acute kidney injury following snake bite envenomation


Mrudul V Dharod, Tushar B Patil, Archana S Deshpande, Ragini V Gulhane, Mangesh B Patil, Yogendra V Bansod 
 Department of Medicine, Government Medical College, Nagpur, Maharashtra, India

Correspondence Address:
Tushar B Patil
Plot No. 9, Rashtrasant Nagar, Godhani Road, Zingabai Takli, Nagpur - 440 030, Maharashtra
India

Background: Snake bite envenomation is a major public health concern in developing countries. Acute kidney injury (AKI) is as important cause of mortality in patients with vasculotoxic snake bite. Aims: This study was to evaluate the clinical profile of snake bite patients and to determine the predictors of developing AKI following snake bite. Materials and Methods: Two hundred and eighty-one patients with snake envenomation were included. Eighty-seven patients developed AKI (Group A) and 194 (Group B) did not. History, examination findings and investigations results were recorded and compared between the two groups. Results: In group A, 61 (70.11%) patients were male and in group B, 117 (60.30%) patients were male. Out of 281 patients, 232 had cellulitis, 113 had bleeding tendencies, 87 had oliguria, 76 had neuroparalysis, and 23 had hypotension at presentation. After multivariate analysis, bite to hospital time (P = 0.016), hypotension (P = 0.000), albuminuria (P = 0.000), bleeding time (P = 0.000), prothrombin time (P = 0.000), hemoglobin (P = 0.000) and total bilirubin (P = 0.010) were significant independent predictors of AKI. Conclusions: AKI developed in 30.96% of patients with snake bite, leading to mortality in 39.08% patients. Factors associated with AKI are bite to hospital time, hypotension, albuminuria, prolonged bleeding time, prolonged prothrombin time, low hemoglobin and a high total bilirubin.


How to cite this article:
Dharod MV, Patil TB, Deshpande AS, Gulhane RV, Patil MB, Bansod YV. Clinical predictors of acute kidney injury following snake bite envenomation.North Am J Med Sci 2013;5:594-599


How to cite this URL:
Dharod MV, Patil TB, Deshpande AS, Gulhane RV, Patil MB, Bansod YV. Clinical predictors of acute kidney injury following snake bite envenomation. North Am J Med Sci [serial online] 2013 [cited 2020 Jul 8 ];5:594-599
Available from: http://www.najms.org/article.asp?issn=1947-2714;year=2013;volume=5;issue=10;spage=594;epage=599;aulast=Dharod;type=0