North American Journal of Medical Sciences

ORIGINAL ARTICLE
Year
: 2013  |  Volume : 5  |  Issue : 1  |  Page : 51--57

Evaluation of total antioxidant capacity of saliva in type 2 diabetic patients with and without periodontal disease: A case-control study


Gowri Pendyala1, Biju Thomas2, Saurabh R Joshi3 
1 Department of Periodontics, Rural Dental College, Loni, Karnataka, India
2 Department of Pedodontics, Rural Dental College, Loni, Karnataka, India
3 Department of Periodontics, A.B. Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India

Correspondence Address:
Gowri Pendyala
Department of Periodontics, Rural Dental College, Loni, Maharashtra
India

Background: Diabetes mellitus (DM) has been linked with oxidative stress and decreased antioxidant defense. A connection has been established between diabetes and periodontal disease. Aim: The aim of present study was to compare salivary total antioxidant capacity of type 2 DM patients and healthy subjects with and without periodontal disease. Materials and Methods: A total of 120 subjects consisting of 30 type 2 DM patients with periodontal disease; 30 type 2 DM patients without periodontal disease; 30 healthy subjects with periodontal disease; 30 healthy subjects without periodontal disease were included in the study. After clinical measurement and samplings, total antioxidant capacity in saliva of type 2 diabetic and healthy subjects were determined, and the data were tested by non-parametric tests. Total antioxidant capacity of the clinical samples was determined spectrophotometrically. Results: The mean salivary total antioxidant capacity was lowest in diabetic patients with periodontitis. Conclusion: Total antioxidant capacity is inversely proportional to the severity of inflammation and can be used as an useful marker of periodontitis in healthy and diabetic patients.


How to cite this article:
Pendyala G, Thomas B, Joshi SR. Evaluation of total antioxidant capacity of saliva in type 2 diabetic patients with and without periodontal disease: A case-control study.North Am J Med Sci 2013;5:51-57


How to cite this URL:
Pendyala G, Thomas B, Joshi SR. Evaluation of total antioxidant capacity of saliva in type 2 diabetic patients with and without periodontal disease: A case-control study. North Am J Med Sci [serial online] 2013 [cited 2020 Aug 14 ];5:51-57
Available from: http://www.najms.org/article.asp?issn=1947-2714;year=2013;volume=5;issue=1;spage=51;epage=57;aulast=Pendyala;type=0