North American Journal of Medical Sciences

ORIGINAL ARTICLE
Year
: 2016  |  Volume : 8  |  Issue : 1  |  Page : 47--55

The association of serum 25-hydroxyvitamin D status in patients with osteoarthritis in the primary care office


Celine Ward1, Krysta Contino1, Akshar Patel1, Eben Eno Mbei1, Satyajeet Roy1, Krystal Hunter2, Shivani Gandhi1 
1 Department of Medicine, Cooper University Hospital, Camden, New Jersey, USA
2 Department of Biostatistics, Cooper Research Institute, Cooper Medical School of Rowan University, Camden, New Jersey, USA

Correspondence Address:
Celine Ward
1484 Village Square, Mount Pleasant, South Carolina - 29464
USA

Background: Low serum 25-hydroxyvitamin D [25(OH)D] and osteoarthritis (OA) are commonly found in patients followed up in a primary care office. Clear evidence to support the link between 25-hydroxyvitamin D levels and OA is lacking. Aim: To describe the association of serum 25-hydroxyvitamin D status in patients with OA in the primary care office. Materials and Methods: We reviewed the records of 1,455 patients seen in our primary care office between November 2013 and October 2014. All patients were older than 18 years and had a diagnosis of OA. Demographic characteristics as well as 25(OH)D levels and comorbidities were analyzed. Results: Levels of 25(OH)D were available in 1,222 patients with OA. Fifty-one percent of the patients had a low 25(OH)D level. Patients with OA and low 25(OH)D were on an average 5 years younger than patients with OA and normal 25(OH)D (P < 0.001). African Americans (71.7%) and Hispanics (63.1%) had a higher prevalence of low 25(OH)D compared to Whites (42.9%) and other races (49.1%) (P < 0.001). There were significantly more smokers (15.4%) and patients with type 2 diabetes (27.6%) in the group of patients with osteoarthritis and low 25(OH)D (P < 0.001). A lower prevalence of hypothyroidism (18.5% versus 27.4%) and higher body mass index (BMI) were also noted in the group of interest. Conclusion: Patients with low levels of 25(OH)D and OA are younger than their counterparts with low 25(OH)D level. Future studies are needed to clarify the relationship between 25(OH)D level and OA.


How to cite this article:
Ward C, Contino K, Patel A, Mbei EE, Roy S, Hunter K, Gandhi S. The association of serum 25-hydroxyvitamin D status in patients with osteoarthritis in the primary care office.North Am J Med Sci 2016;8:47-55


How to cite this URL:
Ward C, Contino K, Patel A, Mbei EE, Roy S, Hunter K, Gandhi S. The association of serum 25-hydroxyvitamin D status in patients with osteoarthritis in the primary care office. North Am J Med Sci [serial online] 2016 [cited 2020 Sep 20 ];8:47-55
Available from: http://www.najms.org/article.asp?issn=1947-2714;year=2016;volume=8;issue=1;spage=47;epage=55;aulast=Ward;type=0