Case Report   OPEN ACCESS

 

Clear cell adenocarcinoma of a female urethra: A case report and review of the literature

 

Amel Trabelsi, MD1, Soumaya Ben Abdelkrim, MD1, Soumaya Rammeh, MD1, Wided Stita, MD1, Nabil Ben Sorba, MD2 Moncef Mokni, MD1, Slim Ben Ahmed, MD3, Sadok Korbi, MD1

Departments of Pathology1 and Oncology3, Farhat Hached Hospital, Sousse, Tunisia.
Department of Urology2, Sahloul Hospital, Sousse, Tunisia.

 

Citation: Trabelsi A, Ben Abdelkrim S, Rammeh S, Stita W, Ben Sorba N, Mokni M, Ben Ahmed S, Korbi S. Clear cell adenocarcinoma of a female urethra: A case report and review of the literature. North Am J Med Sci 2009; 1: 321-323.    
Availability: www.najms.org
ISSN: 1947 – 2714

 

Abstract   

Context: Clear cell adenocarcinoma of the urethra is an extremely rare tumour. Its histogenetic derivation remains controversial. Case report: We report a new case of clear cell adenocarcinoma of the proximal urethra in a 56-year-old woman who presented with grossly hematuria. Urethral cystoscopy revealed a tumour protruding from the posterior urethral wall at the bladder neck. Treatment consisted of urethrocystectomy with pelvic lymph node dissection. Histologically, the neoplasm consisted of clear cell adenocarcinoma of the urethra. Conclusion: It appears that female urethral adenocarcinoma has more than one tissue of origin.

Keywords: Clear cell carcinoma, histopathology, urethra.

Correspondence to: Soumaya Ben Abdelkrim, Department of Pathology, Farhat Hached Hospital, Sousse, Tunisia. Tel.: 21699326546, Fax: 21673226702. Email: benabdelkrims@voila.fr