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  Indian J Med Microbiol
 

Figure 1: a . H&E section demonstrating prominent follicular plugging (blue arrow). b . Erythrocytes sludging in dermal blood vessels and forming linear stacks of erythrocytes called rouleaux (blue arrows). c. Same as b , at higher magnification. d . Positive PAS staining along the BMZ (basement membrane zone) (blue arrow). e. DIF showing positive staining along the epidermal BMZ utilizing FITC conjugated anti-human fibrinogen (yellow arrow); the white arrow highlights cytoplasmic and perinuclear reactivity within epidermal keratinocytes. F. DIF showing positive epidermal staining with FITC conjugated anti-IgG (yellow staining; dark blue arrow). Epidermal keratinocyte nuclei are conterstained with Dapi (light blue). g, DIF showing positive staining along the epidermal BMZ utilizing FITC conjugated anti-human fibrinogen (yellow arrow); the white arrow highlights BMZ reactivity, and the yellow arrow shows vascular reactivity h. DIF showing positive staining with FITC conjugated vomplement/C3 against superficial dermal blood vessels (yellow staining; dark blue arrow) i. IHC demonstrating positive staining against COX-2 in the dermal inflammatory infiltrate, and also in the dermal extracellular matrix (brown staining; blue arrows). j. IHC highlighting positive staining against HLA-DPDQDR in the dermal inflammatory infiltrate (brown staining; blue arrow). k and l, IHCs showing positive staining against ZAP-70 in the dermal inflammatory infiltrate(brown staining; blue arrows).

Figure 1: a . H&E section demonstrating prominent follicular plugging (blue arrow). b . Erythrocytes sludging in dermal blood vessels and forming linear stacks of erythrocytes called rouleaux (blue arrows). c. Same as b , at higher magnification. d . Positive PAS staining along the BMZ (basement membrane zone) (blue arrow). e. DIF showing positive staining along the epidermal BMZ utilizing FITC conjugated anti-human fibrinogen (yellow arrow); the white arrow highlights cytoplasmic and perinuclear reactivity within epidermal keratinocytes. F. DIF showing positive epidermal staining with FITC conjugated anti-IgG (yellow staining; dark blue arrow). Epidermal keratinocyte nuclei are conterstained with Dapi (light blue). g, DIF showing positive staining along the epidermal BMZ utilizing FITC conjugated anti-human fibrinogen (yellow arrow); the white arrow highlights BMZ reactivity, and the yellow arrow shows vascular reactivity h. DIF showing positive staining with FITC conjugated vomplement/C3 against superficial dermal blood vessels (yellow staining; dark blue arrow)  i. IHC demonstrating positive staining against COX-2 in the dermal inflammatory infiltrate, and also in the dermal extracellular matrix (brown staining; blue arrows). j. IHC highlighting positive staining against HLA-DPDQDR in the dermal inflammatory infiltrate (brown staining; blue arrow). k and l, IHCs showing positive staining against ZAP-70 in the dermal inflammatory infiltrate(brown staining; blue arrows).