Figure 1: Exosomes carrying microbial products and protein antigens are localized in the nasal mucosa. The nasal epithelial layer was sampled from patients with chronic rhinitis as described above. The samples were processed for EM. The representative pictures show exosomes stained with antibodies of SEB and Derp1. The larger gold particles (12 nm) indicate the labels of avb6; the smaller gold particles (6 nm) indicate the labels of Derp1. C-D, the gels show the immune blots of Derp1 (C) and SEB (D). The blots of beta-actin were used as internal loading controls. The data represent 3 experiments.