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  Indian J Med Microbiol
 

Figure 1: (a) The effect of doxorubicin on MDA-MB-231 cells by assessing the levels of phosphorylation of AKT at Ser473. Equal amount of cell lysates were on a western blot using the antibody against phosphor-AKT and AKT. Data represent mean from 3 experiments±SD. *Represents significant differences between doxorubicin and doxorubicin+LY292002 samples at P≤0.05 levels. (b) Inhibition of PI3-Akt blocks pCD-induced anti-apoptosis-induced by doxorubicin. Mean from 3 experiments±SD. The AP sample represents transfected cells with deleted activation peptide

Figure 1: (a) The effect of doxorubicin on MDA-MB-231 cells by assessing the levels of phosphorylation of AKT at Ser473. Equal amount of cell lysates were on a western blot using the antibody against phosphor-AKT and AKT. Data represent mean from 3 experiments±SD. *Represents significant differences between doxorubicin and doxorubicin+LY292002 samples at <i>P</i>≤0.05 levels. (b) Inhibition of PI3-Akt blocks pCD-induced anti-apoptosis-induced by doxorubicin. Mean from 3 experiments±SD. The AP sample represents transfected cells with deleted activation peptide