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CASE REPORT
Year : 2013  |  Volume : 5  |  Issue : 12  |  Page : 721-723

Primary adrenal lymphoma with paraneoplastic syndrome


1 Department of Internal Medicine, University of Alabama at Birmingham, WP P230, Birmingham, Alabama 35249-7331, USA
2 Hematology-Oncology, Montgomery Cancer Center, Montgomery, Alabama 36107, USA

Correspondence Address:
Radhika Dasararaju
University of Alabama at Birmingham, WP P230, Birmingham, Alabama 35249-7331, 1Montgomery Cancer Center, Montgomery, Alabama 36107
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1947-2714.123275

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Context: The adrenal gland is a common site for neoplastic diseases and primary adrenal lymphoma (PAL) is a rare tumor with around 120 cases reported so far. Case Report: We present a rare case of 76-year-old male who presented with headache, confusion, inappropriate body movements and abdominal pain. Adrenal biopsy revealed PAL and he has had an excellent neurologic outcome to date with chemotherapy and involved field radiation. Conclusion: The majority of cases of PAL are B cell lymphomas with diffuse large cell in 70% of cases. Clinical symptoms are variable and patients may present with abdominal pain, fever, anorexia, weight loss, fatigue or symptoms of adrenal insufficiency. Therapeutic modalities for PAL include surgery, chemotherapy and radiotherapy and corticosteroid replacement. With this case report, we hope to raise awareness about this rare disease and to include lymphoma in the differential of adrenal masses.


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