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Year : 2014  |  Volume : 6  |  Issue : 11  |  Page : 599-600

Perforated jejunal diverticulum in the use of mycophenolate mofetil

1 Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA
2 SUNY Upstate Medical University, Syracuse, New York, USA
3 Department of Medicine, Bassett Medical Center, Cooperstown, New York, USA

Correspondence Address:
Wisit Cheungpasitporn
Mayo Clinic, Rochester, Minnesota- 55905
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1947-2714.145484

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Context: Jejunal diverticulosis is a rare disease. Common acute complications include diverticulitis, intestinal obstruction, bleeding and perforation. Gastrointestinal tract perorations have also been rarely observed in the use of mycophenolate mofetil. Case Report: We report a 44-year-old man with end-stage renal disease post failed kidney transplant on low-dose mycophenolate mofetil who presented with acute onset of abdominal pain. He was successfully given the diagnosis of perforated jejunal diverticulum. The patient successfully underwent a segmental jejunal resection and anastomosis. He unfortunately developed a recurrent jejunal perforation a month later and again had the second segmental jejunal resection operation. Mycophenolate mofetil then was discontinued. Conclusion: The present case illustrates jejunal diverticulum perforation in the use of mycophenolate mofetil. Physicians should increase the awareness of this association of perforated jejunal diverticulum in patients using mycophenolate mofetil.

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