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Year : 2014  |  Volume : 6  |  Issue : 8  |  Page : 422-424

Marginal zone mucosa associated lymphoid tissue diffuse large B cell lymphoma

1 Department of Internal Medicine, University of Alabama at Birmingham Health Center Montgomery, Alabama, USA
2 Department of Hematology-Oncology, Montgomery Cancer Center, Montgomery, Alabama, USA

Correspondence Address:
Adrian Pedro Noriega Aldave
2055, East S Blvd, Suite 200, Montgomery, Alabama-36116
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1947-2714.139307

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Context: Non-Hodgkin's lymphomas (NHL) primarily involving the orbit, is relatively uncommon. Rarely two pathologically different NHL cell types have been found to be coexistent. Case Report: We report a case of orbital lymphoma in a 62-year-old male with rare histopathological findings secondary to transformation of once cell type into another. Tissue diagnosis and molecular studies led to revelation of diffuse large B cell lymphoma evolving from MALT lymphoma. Conclusion: Proliferation of two morphologically and phenotypically different B cells resulting in malignancy has not been found in the orbit so far. They are usually aggressive tumors and require chemo-immunotherapy.

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