North American Journal of Medical Sciences

ORIGINAL ARTICLE
Year
: 2010  |  Volume : 2  |  Issue : 10  |  Page : 473--477

Prevalence and etiologic agents of female reproductive tract infection among in-patients and out-patients of a tertiary hospital in Benin city, Nigeria


Richard Omoregie1, Christopher Aye Egbe2, Isaac Ohiorenuan Igbarumah2, Helen Ogefere3, Evelyn Okorie2 
1 School of Medical Laboratory Sciences, University of Benin Teaching Hospital, P.M.B. 1111, Benin City, Edo State, Nigeria
2 Department of Medical Microbiology, University of Benin Teaching Hospital, P.M.B. 1111, Benin City, Edo State, Nigeria
3 Department of Medical Laboratory Science, School of Basic Medical Sciences, University of Benin, Benin City, Nigeria

Correspondence Address:
Richard Omoregie
School of Medical Laboratory Sciences, University of Benin Teaching Hospital, P.M.B. 1111, Benin City, Edo State
Nigeria

Background: Reproductive tract infections are public health problems in women of reproductive age and can result in serious consequences if not treated. Aims: To determine the prevalence and causes of reproductive tract infections among in-patients and out-patients attending a tertiary health institution in Benin City. The antimicrobial susceptibility profiles of bacterial agents will also be determined. Patients and methods: High vaginal swabs or endocervical swabs and blood were collected from 957 patients consisting of 755 out-patients and 202 in-patients. The swabs were processed and microbial isolates identified using standard technique. Disc susceptibility tests were also performed on microbial isolates. The blood samples were used for serological diagnosis of syphilis. Results: There was no significant difference in the prevalence of female reproductive tract infections between in-patients (52.48%) and out-patients (47.02%), although in-patients showed a significantly higher risk of developing mixed infections (in-patients vs. out-patients; 34.91% vs. 22.25%, OR = 1.873 95% CI = 1.169, 3.001; P = 0.01). Candida albicans was the most prevalent etiologic agent among out-patients studied while Staphylococcus aureus was the most prevalent etiologic agent among in-patients. Trichomonas vaginalis was observed only among out-patients. Ceftriaxone, ciprofloxacin and ofloxacin were the most active antibacterial agents. Syphilis was not detected in any patient. Conclusion: An overall prevalence of 48.17% of female reproductive tract infection was observed among the study population. Although there was no significant difference between in-patients and out-patients, in-patients appeared to have 1-3-fold increase risk of developing mixed infections. The most prevalent etiologic agent differs between in-patients and out-patients. Despite the high activity of ceftriaxone, ciprofloxacin and ofloxacin against bacterial isolates from both in-patients and out-patients, prudent use of antibacterial agents is advocated.


How to cite this article:
Omoregie R, Egbe CA, Igbarumah IO, Ogefere H, Okorie E. Prevalence and etiologic agents of female reproductive tract infection among in-patients and out-patients of a tertiary hospital in Benin city, Nigeria.North Am J Med Sci 2010;2:473-477


How to cite this URL:
Omoregie R, Egbe CA, Igbarumah IO, Ogefere H, Okorie E. Prevalence and etiologic agents of female reproductive tract infection among in-patients and out-patients of a tertiary hospital in Benin city, Nigeria. North Am J Med Sci [serial online] 2010 [cited 2021 Oct 20 ];2:473-477
Available from: https://www.najms.org/article.asp?issn=1947-2714;year=2010;volume=2;issue=10;spage=473;epage=477;aulast=Omoregie;type=0