North American Journal of Medical Sciences

CASE REPORT
Year
: 2014  |  Volume : 6  |  Issue : 9  |  Page : 484--486

Hemophagocytic lymphohistiocytosis (hlh) associated with t-cell lymphomas: broadening our differential for fever of unknown origin


Sherrie Khadanga1, Benjamin Solomon1, Kim Dittus2 
1 Department of Medicine, University of Vermont, Vermont, USA
2 Division of Hematology/Oncology, University of Vermont, Vermont, USA

Correspondence Address:
Sherrie Khadanga
Department of Medicine, University of Vermont, 111 Colchester Avenue, Fletcher 311, Burlington, Vermont-05401
USA

Context: Hemophagocytic lymphohistiocytosis (HLH), due to the excessive activity of histiocytes and lymphocytes, is a rare but aggressive disease that typically occurs in infancy but can be seen in all ages. If left untreated, patients with HLH may live for only a few months and die from multi-organ failure. Case Report: We present two cases of HLH diagnosis. Fever, spleen, and hepatic abnormalities were noted in both cases. Conclusion: Early diagnosis is the key and these two cases of similar etiology highlight how fever of unknown origin should force us to broaden our differential.


How to cite this article:
Khadanga S, Solomon B, Dittus K. Hemophagocytic lymphohistiocytosis (hlh) associated with t-cell lymphomas: broadening our differential for fever of unknown origin.North Am J Med Sci 2014;6:484-486


How to cite this URL:
Khadanga S, Solomon B, Dittus K. Hemophagocytic lymphohistiocytosis (hlh) associated with t-cell lymphomas: broadening our differential for fever of unknown origin. North Am J Med Sci [serial online] 2014 [cited 2021 Oct 21 ];6:484-486
Available from: https://www.najms.org/article.asp?issn=1947-2714;year=2014;volume=6;issue=9;spage=484;epage=486;aulast=Khadanga;type=0