North American Journal of Medical Sciences

ORIGINAL ARTICLE
Year
: 2015  |  Volume : 7  |  Issue : 6  |  Page : 271--274

Inverse correlation between serum C-reactive protein and magnesium levels in smokers and nonsmokers


Muhamamd Atif Ata1, Shumaila Shabbir Shaikh2, Tehseen Iqbal1, Hina3, Daniyal Jamil1, Rabiya Khan1, Masharib Basheer Qazi1, Telil Riwan1 
1 Department of Biochemistry, Dow University of Health Sciences, Karachi, Pakistan
2 Department of Biochemistry, Isra University, Hyderabad, Pakistan
3 Muhammadi Hospital, Latifabad, Hyderabad, Sindh, Pakistan

Correspondence Address:
Muhamamd Atif Ata
Assistant Professor of Biochemistry, Dow University of Health Sciences, Karachi, Sindh - 74200
Pakistan

Background: Smoking plays a key role in increasing the inflammatory marker C-reactive protein (CRP). Aims: To examine inverse correlation between CRP and magnesium levels in smokers and nonsmokers. Materials and Methods: A total of 192 healthy adult male subjects were included in the present study, out of which 96 were smokers and the remaining 96 were nonsmokers having age range from 20 to 40 years, and all the subjects belonged to District Matyari of Hyderabad. Serum CRP was measured by NycoCard standard kit method and magnesium levels by DiaSys standard kit method in smokers and nonsmokers. Results: The levels of serum CRP in smokers (14.62 ± 0.16 mg/L) is high as compared to nonsmokers (4.81 ± 0.38 mg/L), which is highly significant (P < 0.001). However, inverse results were seen for serum magnesium levels which were significantly higher (P < 0.001) in nonsmokers (2.52 ± 0.18 mg/L) as compared to the smokers (1.09 ± 0.38 mg/dL). A significant (P < 0.001) inverse relationship between serum CRP and magnesium concentrations were seen in smokers. Conclusion: This result shows that smoking increases serum CRP, an inflammatory marker parallel to decrease in serum magnesium levels in smokers having 20-40 years of age.


How to cite this article:
Ata MA, Shaikh SS, Iqbal T, Hina, Jamil D, Khan R, Qazi MB, Riwan T. Inverse correlation between serum C-reactive protein and magnesium levels in smokers and nonsmokers.North Am J Med Sci 2015;7:271-274


How to cite this URL:
Ata MA, Shaikh SS, Iqbal T, Hina, Jamil D, Khan R, Qazi MB, Riwan T. Inverse correlation between serum C-reactive protein and magnesium levels in smokers and nonsmokers. North Am J Med Sci [serial online] 2015 [cited 2021 May 11 ];7:271-274
Available from: https://www.najms.org/article.asp?issn=1947-2714;year=2015;volume=7;issue=6;spage=271;epage=274;aulast=Ata;type=0