North American Journal of Medical Sciences

ORIGINAL ARTICLE
Year
: 2016  |  Volume : 8  |  Issue : 1  |  Page : 31--39

Association of comorbid and metabolic factors with optimal control of type 2 diabetes mellitus


Satyajeet Roy1, Anthony Sherman1, Mary Joan Monari-Sparks1, Olga Schweiker1, Navjot Jain1, Etty Sims1, Michelle Breda1, Gita P Byraiah1, Ryan George Belecanech1, Michael Domenic Coletta1, Cristian Javier Barrios1, Krystal Hunter2, John P Gaughan2 
1 Department of Medicine, Cooper University Hospital, Camden, New Jersey, USA
2 Department of Biostatistics, Cooper Research Institute, Cooper Medical School of Rowan University, Camden, New Jersey, USA

Correspondence Address:
Satyajeet Roy
Department of Medicine, Cooper University Hospital, Cooper Medical School of Rowan University, 1103 North Kings Highway, Suite 203, Cherry Hill, New Jersey
USA

Background: Type 2 diabetes mellitus (T2DM) is a poorly controlled epidemic worldwide that demands active research into mitigation of the factors that are associated with poor control. Aims: The study was to determine the factors associated with suboptimal glycemic control. Materials and Methods: Electronic medical records of 263 adult patients with T2DM in our suburban internal medicine office were reviewed. Patients were divided into two groups: Group 1 [optimal diabetes control with glycosylated hemoglobin (HbA1c) of 7% or less] and Group 2 (suboptimal diabetes control with HbA1c greater than 7%). The influence of factors such as age, gender, race, social history, comorbid conditions, gestational diabetes, family history of diabetes, diabetes management, statin use, aspirin use, angiotensin convertase enzyme inhibitor (ACE-I) or angiotensin receptor blocker (ARB) use, body mass index (BMI), blood pressures, lipid profile, and urine microalbumin level were analyzed in the two groups. Results: In the suboptimal diabetes control group (N = 119), the majority (86.6%) of the patients were 41-80 years old. Factors associated with the suboptimal control were male gender [odds ratio (OR) 2.6, 95% confidence interval (CI), 1.579-4.321], Asian ethnicity (OR 1.4, 95% CI, 0.683-3.008), history of peripheral arterial disease (PAD; OR 3.9, 95% CI, 1.017-14.543), history of congestive heart failure (CHF; OR 3.9, 95% CI, 1.017-14.543), elevated triglycerides (OR 1.004, 95% CI, 1.000-1.007), and elevated urine microalbumin level of 30 mg/24 h or above (OR 4.5, 95% CI, 2.446-8.380). Patients with suboptimal diabetes control had a 3.8 times greater odds (95% CI, 1.493-6.885) of receiving the insulin and oral hypoglycemic agent together. Conclusions: In adult patients with T2DM, male gender, Asian ethnicity, CHF, PAD, management with insulin along with oral hypoglycemic agents, hypertriglyceridemia, and microalbuminuria were associated with suboptimal control.


How to cite this article:
Roy S, Sherman A, Monari-Sparks MJ, Schweiker O, Jain N, Sims E, Breda M, Byraiah GP, Belecanech RG, Coletta MD, Barrios CJ, Hunter K, Gaughan JP. Association of comorbid and metabolic factors with optimal control of type 2 diabetes mellitus.North Am J Med Sci 2016;8:31-39


How to cite this URL:
Roy S, Sherman A, Monari-Sparks MJ, Schweiker O, Jain N, Sims E, Breda M, Byraiah GP, Belecanech RG, Coletta MD, Barrios CJ, Hunter K, Gaughan JP. Association of comorbid and metabolic factors with optimal control of type 2 diabetes mellitus. North Am J Med Sci [serial online] 2016 [cited 2021 Oct 28 ];8:31-39
Available from: https://www.najms.org/article.asp?issn=1947-2714;year=2016;volume=8;issue=1;spage=31;epage=39;aulast=Roy;type=0