CASE REPORT
Year : 2016 | Volume
: 8 | Issue : 7 | Page : 312--315
Selective serotonin-norepinephrine reuptake inhibitors-induced Takotsubo cardiomyopathy
Rahul Vasudev1, Upamanyu Rampal2, Hiten Patel2, Kunal Patel2, Mahesh Bikkina2, Fayez Shamoon2
1 Department of Internal Medicine, New York Medical College, St Joseph's Regional Medical Center, New Jersey, USA
2 Department of Cardiology, New York Medical College, St Joseph's Regional Medical Center, New Jersey, USA
Correspondence Address:
Rahul Vasudev
Department of Internal Medicine, New York Medical College, St Joseph«SQ»s Regional Medical Center, New Jersey - 07503
USA
Context: Takotsubo translates to «DQ»octopus pot«DQ» in Japanese. Takotsubo cardiomyopathy (TTC) is characterized by a transient regional systolic dysfunction of the left ventricle. Catecholamine excess is the one most studied and favored theories explaining the pathophysiology of TTC. Case Report: We present the case of a 52-year-old Hispanic female admitted for venlafaxine-induced TTC with a review literature on all the cases of Serotonin-norepinephrine reuptake inhibitors (SNRI)-associated TTC published so far. Conclusion: SNRI inhibit the reuptake of catecholamines into the presynaptic neuron, resulting in a net gain in the concentration of epinephrine and serotonin in the neuronal synapses and causing iatrogenic catecholamine excess, ultimately leading to TTC.
How to cite this article:
Vasudev R, Rampal U, Patel H, Patel K, Bikkina M, Shamoon F. Selective serotonin-norepinephrine reuptake inhibitors-induced Takotsubo cardiomyopathy.North Am J Med Sci 2016;8:312-315
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How to cite this URL:
Vasudev R, Rampal U, Patel H, Patel K, Bikkina M, Shamoon F. Selective serotonin-norepinephrine reuptake inhibitors-induced Takotsubo cardiomyopathy. North Am J Med Sci [serial online] 2016 [cited 2021 Dec 8 ];8:312-315
Available from: https://www.najms.org/article.asp?issn=1947-2714;year=2016;volume=8;issue=7;spage=312;epage=315;aulast=Vasudev;type=0 |
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